Principia medicinae, epitome, et totius humani corporis fabrica seu ex microcosmi armonia divinum, germen,
A 1685 Latin medical treatise printed in Mexico City by the heirs of Bernardo Calderón, compiling physiology and aphorisms by Diego Osorio y Peralta, Niccolò Leoniceno and Hippocrates for physicians and students. The pictures are letterpress pages with dense black roman and italic type, an ornate large initial, a small decorative printer's ornament, and a framed woodcut of a standing Virgin with a radiating mandorla, offering strong contrast blocks, ornamental borders and classical printed type layouts.
