De ligno sancto non permiscendo,
A 1540 Paris medical treatise by Antoine Lecoq on guaiac wood, printed by Simon de Colines and held by the John Carter Brown Library, written for physicians and students of the period. Its pictures are small woodcut pieces: a densely patterned initial letter C with scrolling foliage, birds and grotesque heads, and a winged figure of Tempus holding a scythe above a Latin motto, useful to a designer for compact ornamental framing and emblematic border work.

