Disputatio medica inauguralis de colica ...
A 1675 Latin medical dissertation on colic, written by Joannes Ericus Oldenborch and printed at Altdorf by Henrici Meyeri for university-trained physicians and students. The single picture shows a large decorated initial E beside the first lines of dense black-letter text, with ornate foliate interlace inside the letter that a designer could borrow for historical initial caps and border patterns.
