The American journal of the medical sciences
A medical journal from 1827 published in the United States, aimed at physicians and medical students, and represented here by pen-and-ink microscopic plates. The pictures are hand-drawn cell and tissue studies with lettered leader lines (a, b, c, d, e, f) keyed to the text, showing star-shaped cells, rounded nuclei, and fibrous networks in sparse black linework on cream paper. A designer could take from them the look of early scientific diagrams: fine hatching, labelled callouts and organic, cell-like abstract forms.
