Practica Alexandri yatros ... cum optimis declarationibus Jacobi de partibus et Simonis Januensis in margine condecenter situatis...
A 1522 Venice medical treatise by Alexander of Tralles, printed by the heirs of O. Scotus with marginal commentaries by Jacob de Partibus and Simon of Genoa for physicians and students. The pages are dense black-letter text in long justified columns, with a few decorated initials and a title page set in large display capitals. A designer might take the contrast of heavy blackletter blocks against small marginal notes, and the ornate hand-drawn initials as models for layout and drop-cap work.
